10-hydroxycamptothecin By Xi'an Wild Whit Biotechnology Co.,ltd.

We are instrumental in manufacturing and supplying to our valuable customers excellent quality 10-Hydroxycamptothecin which is available with following specification:-
1. Product name: 10-hydroxycamptothecine
2. Active ingredient:Camptothecin
3. Botanical source: Camptotheca acuminata Decne
4. Part of the plant used:Seed
5. CAS NO.: 19685-09-7
6. Specification: 95% 98% 99%
7. Molecular formula: C20H16N2O5
8. Molecular Weight: 364.35
9. Appearance: Light Yellow Crystal powder
10. Usage: Pharmaceuticals, healthcares
11. Test method: HPLC
12. Solubility:Clear Yellow Solution at 1Mg/Ml in Dimethylsulfoxide

10-hydroxycamptothecin is the derivative of camptothecine that is a micro-alkaloid from camptotheca Acuminate (a tree native to mainland China). is a kind of pharmaceutical intermediate, an alkaloid originally isolated from the Camptotheca acuminata, exerted inhibitory effects on DNA topoisomerase (Topo )[1]and has anticancer activity in vitro and in vivo. It can also induce differentiation of leukemia MELC[2]and HL-60[3]cells. The purpose of this study is to investigate the proliferation-inhibiting and differentiation-inducing actions of HCPT on human hepatoma Hep G2 cells.