Product Overview
Key Features
88150-42-9
Chemical Formula
C20H25ClN2O5
For the treatment of hypertension and chronic stable angina.Amlodipine decreases arterial smooth muscle contractility and subsequent vasoconstriction by inhibiting the influx of calcium ions through L-type calcium channels. Calcium ions entering the cell through these channels bind to calmodulin. Calcium-bound calmodulin then binds to and activates myosin light chain kinase (MLCK). Activated MLCK catalyzes the phosphorylation of the regulatory light chain subunit of myosin, a key step in muscle contraction. Signal amplification is achieved by calcium-induced calcium release from the sarcoplasmic reticulum through ryanodine receptors. Inhibition of the initial influx of calcium decreases the contractile activity of arterial smooth muscle cells and results in vasodilation. The vasodilatory effects of amlodipine result in an overall decrease in blood pressure. Amlodipine is a long-acting CCB that may be used to treat mild to moderate essential hypertension and exertion-related angina (chronic stable angina). Another possible mechanism is that amlodipine inhibits vascular smooth muscle carbonic anhydrase I activity causing cellular pH increases which may be involved in regulating intracelluar calcium influx through calcium channels.
Product Specifications
Drug Type | Medicine Raw Materials |
Physical Form | Powder |
FOB Port | mumbai |
Payment Terms | Cheque, Telegraphic Transfer (T/T), Paypal |
Supply Ability | 100 Per Week |
Delivery Time | 1 Week |
Main Export Market(s) | Western Europe, Australia, North America, Eastern Europe, Middle East, Africa, Central America, South America, Asia |
Main Domestic Market | All India |
Company Details
Wholesaler, Trader, Distributors and supplier of Pharmaceutical finish formulation, Raw materials, intermediates, Excipients, Ayurvedic products. we are supplying generic medicines for almost all of the therapeutic classes such as Antiviral, Antimalarial, Antifungal, Anticancer (Oncology), Erectile Dysfunction, Sex Enhancement, Cardiovascular, Beta-lactamAntibiotics, NSAIDs, Antidiabetic, Antiasthmatic, Antiemetic, Anesthetic, Antacid, Painkillers, Antiallergic, Antihypertensive, Dermatological, Ophthalmic, Gastricmedicines in the form of Coated and Uncoated Tablets, Effervescent Tablets, Sustained Release (SR) Tablets, Chewable Tablets, Flavored Tablets,Capsules, Derma Care,Transdermals, Topical Preparations, Dry Syrups, Vials,Oral Liquids, Suspension, Gel, Creams, Lotions, Ointments, Dry Injections, Drops, Inhalers andExternal Formulations.
Business Type
Exporter, Manufacturer, Distributor, Supplier, Trading Company
Employee Count
30
Establishment
2018
Working Days
Monday To Sunday
GST NO
24AOKPV4993D2ZG
Payment Mode
Telegraphic Transfer (T/T)
Seller Details
KAVYA PHARMA
GST
24AOKPV4993D2ZG
Rating
4
Proprietor
Ms. Kavya
Member Since
6 Years
AddressView on Map
Shop No - 215, 2nd Floor, Aaimata Road, Raj Mandir Complex, Parvat Patiya, Surat, Gujarat, 395010, India
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