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Epirubicin is an anthracycline drug used for chemotherapy. It is marketed by Pfizer under the trade name Ellence in the US and Pharmorubicin or Epirub...View Product Details
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Key Features
Epirubicin is an anthracycline drug used for chemotherapy. It is marketed by Pfizer under the trade name Ellence in the US and Pharmorubicin or Epirubicin Ebewe elsewhere.
Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death. Binding to cell membranes and plasma proteins may be involved in the compound's cytotoxic effects. Epirubicin also generates free radicals that cause cell and DNA damage.
Epirubicin is favoured over doxorubicin, the most popular anthracycline, in some chemotherapy regimens as it appears to cause fewer side-effects. Epirubicin has a different spatial orientation of the hydroxyl group at the 4' carbon of the sugar, which may account for its faster elimination and reduced toxicity. Epirubicin is primarily used against breast and ovarian cancer, gastric cancer, lung cancer, and lymphomas.
Similarly to other anthracyclines, epirubicin acts by intercalating DNA strands. Intercalation results in complex formation which inhibits DNA and RNA synthesis. It also triggers DNA cleavage by topoisomerase II, resulting in mechanisms that lead to cell death. Binding to cell membranes and plasma proteins may be involved in the compound's cytotoxic effects. Epirubicin also generates free radicals that cause cell and DNA damage.
Epirubicin is favoured over doxorubicin, the most popular anthracycline, in some chemotherapy regimens as it appears to cause fewer side-effects. Epirubicin has a different spatial orientation of the hydroxyl group at the 4' carbon of the sugar, which may account for its faster elimination and reduced toxicity. Epirubicin is primarily used against breast and ovarian cancer, gastric cancer, lung cancer, and lymphomas.
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Company Details
LeeHPL VENTURES PVT. LTD., Established in 2012 at Nagpur in Maharashtra, is a leading Exporter,Supplier,Trading Company of Pharmaceutical Ointments & Creams in India. LeeHPL VENTURES PVT. LTD. is one of Trade India's verified and trusted sellers of listed products. With extensive experience in supplying and trading Epithra , LeeHPL VENTURES PVT. LTD. has made a reputed name for itself in the market with high-quality Magestrol Acetate Tablets, ABAMUNE 300 MG, ABAVIR 300 MG TABLET, etc.
Focusing on a customer-centric approach, LeeHPL VENTURES PVT. LTD. has a pan-India presence and caters to a huge consumer base throughout the country. Buy Pharmaceutical Ointments & Creams in bulk from LeeHPL VENTURES PVT. LTD. at Trade India quality-assured products.
Focusing on a customer-centric approach, LeeHPL VENTURES PVT. LTD. has a pan-India presence and caters to a huge consumer base throughout the country. Buy Pharmaceutical Ointments & Creams in bulk from LeeHPL VENTURES PVT. LTD. at Trade India quality-assured products.
Business Type
Exporter, Supplier, Trading Company
Establishment
2012
Working Days
Monday To Sunday
Seller Details
L
LeeHPL VENTURES PVT. LTD.
Director
Mr. Anil Gangwani
Address
Shop No. 2, Ashok Nagar, Lakadganj, Nagpur, Maharashtra, 440008, India
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