Hbt1 Cas No.i 489408-02-8 99.0 % Purity Min. For Nootropics Enhance Learning Ability.

Product nameHBT1
Other nameYDL223C
CAS No.489408-02-8
Molecular formulaC16H17F3N4O2S
Molecular weight386.40
Purity99.0%
AppearanceLight yellow solid
Packing1kg per bag 25kg per drum
Applicationnootropics
3.Product introduction
HBT1 binds to the ligand-binding domain of I -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) in a glutamate-dependent manner. This means that HBT1 is a molecule that can only bind to a specific site on the AMPA-R protein when glutamate is present, and this binding helps regulate the activity of the protein.
AMPA receptors are expressed throughout the central nervous system and play important roles in neuronal communication, sensory processing, learning, memory, and synaptic plasticity. AMPA receptors are major contributors to excitatory neurotransmission, mediate rapid, rapidly desensitizing excitation at many synapses, and are involved in early responses to glutamate in synaptic regions.
4.Application
HBT1 is a novel AMPA receptor potentiator that is less agonistic than LY451395 and OXP1, induces the production of brain-derived neurotrophic factor (BDNF), and has minimal agonistic effects on primary neurons. HBT1 binds to the ligand-binding domain of AMPA-R in a glutamate-dependent manner. Together, they promote synaptic plasticity processes involved in learning, memory, excitability, and neuroprotection. It can improve the brain's cognitive ability and memory, and enhance people's learning ability.