Embroidered Simianization Of Non-monkey Antibodies

We are the leading service provider involved in rendering services of Simianization of Non-monkey Antibodies. Creative Biolabs has launched a novel service of Simianization of Non-monkey Antibodies.
In comparison with rodents and rabbits, monkey (NHP) are large animals with a genetic background closer to that of humans. Monkey versions of monoclonal antibodies are of paramount value in evaluating a therapeutic antibody in monkey (NHP) animal models. Relying our years of experience in antibody humanization and phage display antibody library technologies, scientists at Creative Biolabs have built up a platform to covert non-monkey monoclonal antibodies into monkey antibodies, so called antibody simianization. This service is mainly achieved by CDR grafting followed by phage display antibody library based back mutation. Monoclonal antibodies derived from a variety of species, such as human, rabbit, chicken, mouse, rat, dog and cow, can be converted into simian antibodies using the same approach. Antibody specificity and affinity are well preserved after simianization.