Acyclovir Injection 500mg By Facmed Pharmaceuticals Pvt. Ltd.

Product Name: Acyclovir Injection 500mg
Indications for Acyclovir Inj:
Genital herpes (severe initial episodes in immunocompetent patients). Herpes simplex (in neonates, and as initial and recurrent treatment in immunocompromised patients). Herpes simplex encephalitis. Varicella zoster (immunocompromised patients).

Adult:
Give by IV infusion over 1 hour. Mucocutaneous herpes simplex (immunocompromised): 5mg/kg every 8 hours for 7 days. Genital herpes: 5mg/kg every 8 hours for 5 days. Encephalitis: 10mg/kg every 8 hours for 10 days. Varicella zoster (immunocompromised): 10mg/kg every 8 hours for 7 days. All: max 20mg/kg every 8 hours. Obese: dose based on ideal body weight. Renal impairment: CrCl 25-50mL/min: give dose every 12 hours; CrCl 10-25mL/min: give dose every 24 hours; CrCl<10mL/min: reduce dose by 50% and give every 24 hours. Coincide a dose for after hemodialysis.

Children:
Give by IV infusion over 1 hour. Neonatal (birth-3mos) herpes simplex: 10mg/kg every 8 hours for 10 days (doses of 15-20mg/kg every 8 hours have been used; see literature). Mucocutaneous herpes simplex (immunocompromised): 10mg/kg every 8 hours for 7 days. Encephalitis: 3mos-12yrs: 20mg/kg every 8 hours for 10 days. Varicella zoster: <12yrs (immunocompromised): 20mg/kg every 8 hours for 7 days. All: max 20mg/kg every 8 hours. Obese: dose based on ideal body weight. Renal impairment: CrCl 25-50mL/min: give dose every 12 hours; CrCl 10-25mL/min: give dose every 24 hours; CrCl <10mL/min: reduce dose by 50% and give dose every 24 hours. Coincide a dose for after hemodialysis.

Contraindications:
Valacyclovir hypersensitivity.

Warnings/Precautions:
Renal impairment: see literature. Maintain adequate hydration. Neurological or serious renal, hepatic, or electrolyte abnormalities, or significant hypoxia. Elderly. Pregnancy (Cat.B). Nursing mothers.

Interactions:
Avoid nephrotoxic drugs. Potentiated by probenecid.

Pharmacological Class:
Nucleoside analogue.

Adverse Reactions:
Inj site reactions, transient elevated BUN and serum creatinine, GI upset, pruritus, rash, CNS effects (esp. in elderly), elevated transaminases, hematologic abnormalities, renal failure, thrombotic thrombocytopenic purpura/hemolytic uremic syndrome in immunocompromised patients.

Features:
1) Sterile
2) WHO GMP Approved Plant
3) Customized packaging available
4) Testing as per BP and USP

Minimum Order Quantity: 3000 packs

Technical Specifications
Brand : Facmed
Usage : Infusion
Strength : 500 mg
Storage Conditions : Store It At Room Temperature
Packaging Type : Vial
Features : WHO-GMP Certified, Highly Effective, Stability, Balanced Composition, Hygienically Packed