Diacerein Ip/bp/usp Medicine Raw Materials

Niksan Pharmaceutical is the largest manufacturer and exporter of the Diacerein among all over the world. Niksan Pharmaceutical is one of biggest the supplier, manufacturer, exporter and distributor of the Diacerein API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.
Niksan Pharmaceutical provides API and finished formulations of Diacerein in all over Indian states Like Kerala, Gujarat,Madhya Pradesh, Uttar Pradesh, Rajasthan, Haryana, , Assam, Punjab, Delhi, Bihar,Rajasthan, Karnataka, Meghalaya, Tamilnadu, Goa, Sikkim, Jammu Kashmir Etc.
Niksan pharmaceutical is also large exporter of the API and finished pharmaceutical products of Diacerein in many countries for years. The countries where we exporting are Myanmar (Burma), Nepal, Vietnam, Pakistan, India, Bangladesh, Egypt, Kuwait, Greece, Israel , Malaysia, Thailand, Indonesia, Austria, Australia, Brazil, Germany, United Kingdom, United States, Japan and many more countries.
Diacerein is one type of anthraquinone class of medicine. Diacerein normally used in joint pain related treatment. Diacerein used in conditions like gout, osteoarthritis, joint pain, and also used in the treatment of swollen joints, bones and stops the degradation of muscles.
SYNONYMS: Diacerein, DiacereA-na.

IUPAC NAME: 4,5-bis(acetyloxy)-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

CAS NO: 13739-02-1

FORMULA: C19H12O8

MOLECURAL MASS: 368.29 ga cmola 1

STORAGE CONDITIONS: Store in cool and dry place. Place medicine away from direct heat and sun light. Dona t put medicine in humid place. Keep away from children and pets.

HOW TO USE DIACEREIN:Take medication orally with or without food.If you have any confusion, kindly contact your doctor.Take medication regularly for the more benefits.

HOW DIACEREIN WORKS:Diacerein reduces the joint pain by inhibiting the interleukin-1 beta receptor. Diacerein also decreases the inflammation and also corrects the altered osteoblast activity.

PHARMACOKINETICS:Only 25% of Diacerein absorbed after the oral administration.The bioavaibility of Diacerein is between 50-60%.The biological half-life Diacerein is 4-10hrs.Almost 53% of Diacerein is excreted by faces and 37% of Diacerein eliminated by the urination.

SIDE EFFECTS OF DIACEREIN:The most common side effects of Diacerein are GI problems.Nausea, vomiting and discomfort of stomach also seen in some patients.The other side effects like soft stool and loose motion also seen in the patients.The other side effects like abnormality of liver and kidney functions are the major side effects of Diacerein.

PRECAUTIONS:Tell your doctor if you have allergic reaction to the Diacerein.If you have any disease like heart disease, kidney problem, liver problem, GI problem tell your doctor before writing prescription.The capsules should be swallowed whole without opening or breaking.If you are pregnant kingly avoid taking the medication.

CDSCO APPROVAL: Celecoxib 100/200mg +Diacerein 50/50mg approved by CDSCO in Indian in 19.07.2010,
Diacerein Modified Release Capsule approved by CDSCO in Indian in 100mg 20.11.2009.

FORMULATIONS AVAILABLE IN MARKET:
Diacerein 50mg capsules
Diacerein 50mg + Curcumin 50mg capsules
Diacerein 50mg + Celecoxib 100 tablets
Diacerein 50mg + Celecoxib 200 tablets
Diacerein 50mg + Aceclofenac 100mg tablets

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult