Miconazole Nitrate Ip/bp/usp/ep Application: Medicine

Niksan Pharmaceutical is the worldAcA A s top most pharmaceutical company who manufactures, supplies and exports of Miconazole Nitrate among the all the pharmaceutical companies. We provide Miconazole Nitrate API and finished formulations to our customers as well as our group companies. Our product Miconazole Nitrate is esteemed and praised by clients and also by other companies.
Niksan Pharmaceutical is the largest manufacturer, trader and supplierand exporter of Miconazole Nitrate in all-over Ankleshwar, Gujarat, India.
Niksan Pharmaceutical manufactures and supplies the Miconazole Nitrate product to the Indian states like Maharashtra, Meghalaya, Tamilnadu, Kerala, Gujarat,Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Karnataka, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan, Karnataka, and other states.
Niksan Pharmaceutical is manufacturer , supplier and exporter of Miconazole Nitrate in many countries from many years like Indonesia, United Arab Emirates, United States, Malaysia, Philippines, United Kingdom, Saudi Arabia, Canada, Australia, Israel, Netherlands, Thailand, Malaysia, Belgium, France, Algeria, Morocco, Netherland, Canada, united states, United Kingdom, Switzerland, Congo, Philippines, Colombia and Germany, Cyprus, Nigeria, Rwanda, South Africa, Denmark, Slovenia, Bolivia, Japan, Uganda, Uzbekistan, Cameroon, Netherlands, Azerbaijan, Venezuela, Morocco, Cote D Ivoire, Turkey, Pakistan, Slovenia, Ireland, Zambia, Poland, Hungary, Ireland, Austria, St Lucia, South Korea, Malawi, Croatia, Malta, Kazakistan, Indonesia, Vietnam, Australia, Hungary, Finland, Sweden, Canada, Australia, United kingdom, Ukraine, Russia, France and many more countries.

MiconazoleNitrate belongs to the class called azoles. Miconazole Nitrate is the medicine used to prevent the fungal infections. Miconazole Nitrate is used as an antifungal agent to treat the fungal infection on vagina and skin.

SYNONYMS: Miconazol, Miconazole, Miconazolum

IUPAC NAME: 1-{2-[(2, 4-Dichlorobenzyl) oxy]-2-(2, 4-dichlorophenyl)ethyl}-1H-imidazole nitrate
CAS NO: 22832-87-7
FORMULA: C18H15Cl4N3O4
MOLECULAR MASS: 479.1 g/mol

STORAGE CONDITIONS: Store the medicine in cool and dry place, away from direct light and heat. Do not place medicine in bathroom or any humid place. Do not put the cap open. Keep away from children and pets.

HOW TO USE: Wash and dry the part of skin where this cream has to apply. Apply this medicine 2 times per day. If you use Miconazole spray, kindly shake the container before using it.

HOW MICONAZOLE WORKS: Miconazole works by inhibiting the CYP450anzyme which is used to build the fungal cell wall. By the inhibition of synthesis of cell wall, the fungal growth stops and by this Miconazole kills the fungal cells.

PHARMACOKINETICS: Miconazole have poor absorption in the systemic circulation. Miconazole takes 18.4 hours to reach the peak plasma concentration. Miconazole metabolism occurs in liver and it does not affect any other activity. The half-life of Miconazole is 24 hours. Less than 1% of Miconazole recovered in urine. And the elimination of Miconazole had done by both urine and feces.

SIDE EFFECTS: Side effects like swelling, redness, itching, irritation of skin, burning are caused by Miconazole. If you see side effects like open sores, blistering of skin, contact your doctor. Seek immediate doctor attention if you see side effects like rash, swelling of skin, Redness, trouble in breathing and dizziness.

PRECAUTION: Tell your doctor if you have any allergic reaction to Miconazole. Before taking the medication tell your doctor about your medical history. Do not take medication if you are in pregnancy or lactation period.

CDSCO APPROVAL: Miconazole Nitrate approved by CDSCO in India in 1979-March,
Miconazole Nitrate approved by CDSCO in India in 1975-August,
Nadifloxacin (1%) + Miconazole Nitrate (2%) + Mometasone Furoate (0.1%) Cream approved by CDSCO in India in 06.06.2006,
Miconazole Nitrate approved by CDSCO in India in 1978-June.

FORMULATION AVAILABLE IN MARKET:
Miconazole Nitrate 2%w/w cream
Miconazole Nitrate 2%w/v gel
Miconazole Nitrate 200mg tablets
Miconazole Nitrate 100mg tablets
Nadifloxacin (1%) + Miconazole Nitrate (2%) + Mometasone Furoate (0.1%) Cream
Gentamycin 0.1% w/w +Miconazole 2%w/w cream
Gentamycin 0.1% w/v + Miconazole 2%w/v cream gel
Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk

REFERENCES:

www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult