Organic Chemistry

Review:
'What strikes the reader straight away is the way the text is laid out so
that it is visually exciting. ...I could go on, so let me end by congratulating
the authors and publishers in producing what I am sure will become the standard
text in organic chemistry. Perhaps I should just summarise how I felt about the
book when I came to put it down: refreshing, exciting and motivational. Tony
Barrett, Imperial College London' -
'"The authors should be congratulated for compiling a book that should prove
very popular with our students...the text is very comprehensive and covers key
areas in a very attractive and user friendly way. Thank you to OUP for
publishing the book at a really good price". Dr Don Green, University of North
London.' - Readership: Major course text suitable for adoption for all mainstream
undergraduate organic chemistry courses for use from the beginning/introductory
level.



Contents


1. What is organic chemistry?
2. Organic structures
3. Determining organic structures
4. Structure of molecules
5. Organic reactions
6. Nucleophilic addition to the carbonyl group
7. Delocalization and conjugation
8. Acidity, basicity, and pKa
9. Using organometallic reagents to make C-C bonds

10. Conjugate addition
11. Proton nuclear magnetic resonance
12. Nucleophilic substitution at the carbonyl (C=O)
group
13. Equilibria, rates, and mechanisms: summary of mechanistic
principles
14. Nucleophilic substitution at C=O with loss of carbonyl
oxygen
15. Review of spectroscopic methods
16. Stereochemistry
17. Nucleophilic substitution at saturated carbon

18. Conformational analysis
19. Elimination reactions
20. Electrophilic addition to alkenes
21. Formation and reactions of enols and enolates

22. Electrophilic aromatic substitution
23. Electrophilic alkenes
24. Chemoselectivity: selective reactions and
protection
25. Synthesis in action
26. Alkylation of enolates
27. Reactions of enolates with aldehydes and ketones: the
aldol reaction
28. Acylation at carbon
29. Conjugate addition of enolates
30. Retrosynthetic analysis
31. Controlling the geometry of double bonds
32. Determination of stereochemistry by spectroscopic
methods
33. Stereoselective reactions of cyclic compounds

34. Diastereoselectivity
35. Pericyclic reactions 1: cycloadditions
36. Pericyclic reactions 2: sigmatropic and electrocyclic
reactions
37. Rearrangements
38. Fragmentation
39. Radical reactions
40. Synthesis and reactions of carbenes
41. Determining reaction mechanisms
42. Saturated heterocycles and stereoelectronics

43. Aromatic heterocycles 1: structures and reactions

44. Aromatic heterocycles 2: synthesis
45. Asymmetric synthesis
46. Organo-main-group chemistry I: sulfur
47. Organo-main-group chemistry II: boron, silicon, and
tin
48. Organometallic chemistry
49. The chemistry of life
50. Mechanisms in biological chemistry
51. Natural products
52. Polymerization
53. Organic chemistry today
Index




Authors, editors, and contributors


Jonathan Clayden, Lecturer in
Organic Chemistry, Manchester University, Nick Greeves, Lecturer in Organic Chemistry,
Liverpool University, Stuart Warren,
Lecturer in Organic Chemistry, and Peter
Wothers, Lecturer in Organic Chemistry, both at Cambridge
University