Tadalafil Ip/bp/ep/usp Cas No: 171596-29-5

Niksan Pharmaceutical is top leading manufacturer, supplier, exporter and trader of Tadalafil in Indian states and also in world other countries. Tadalafil is the best product of Niksan Pharmaceutical which exporting as a form of API and finished formulation.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader in the domestic level as well as the international market.

Niksan is an Indian based pharmaceutical company so it also supplies and manufactures the Tadalafil to all Indian states like Gujarat, Maharashtra, Punjab, Delhi, Tamilnadu, Goa, Uttar Pradesh, Karnataka, Jammu&Kashmir, West Bengal, Assam, Rajasthan, Hyderabad, Karnataka, Kerala, Madhya Pradesh, Manipur, Meghalaya, Mizoram, Nagaland, Orissa, Punjab and Haryana.

Niksan Pharmaceutical and Niksan group companies are exporters, suppliers and manufacturers of the API and also Tadalafil formulations in many countries for many years. Niksan pharmaceutical currently exports Tadalafil API and Formulation to countries like Nicaragua, Paraguay, St Helena, Guatemala, Dominican Republic, Bangladesh, Lebanon, Honduras, Nigeria, Brazil, Uruguay, Germany, Italy, Mexico, Bahamas, Bahrain, Barbados, Republic of Korea (South Korea), Republic of the Congo, Romania, Russia, Rwanda, Sierra Leone, Singapore, Slovakia, Slovenia and more other countries.

Tadalafil is a medicine which is used to control high blood pressure.
Tadalafil is used in treatment of erectile dysfunction and an enlarged prostate.

SYNONYMS: Tadalafil, Tadalafilo

IUPAC NAME: (2R, 8R)-2-(2H-1, 3-benzodioxol-5-yl)-6-methyl-3, 6, 17-triazatetracyclo heptadeca-1(10), 11, 13, 15-tetraene-4, 7-Dione

CAS NO: 171596-29-5

FORMULA: C22H19N3O4

MOLECULAR MASS: 389.40 g/mol

STORAGE OF TADALAFIL: Keep your tablets in the original pack. Keep tablet in cool and dry place. Do not store Torsemide in the bathroom or near a sink.

APPLICATIONS OF TADALAFIL: Tadalafil is used to treatment of male sexual function problems. Tadalafil does not give protection against sexually transmitted diseases like HIV, gonorrhoea and hepatitis B.

HOW TO USE: Tadalafil is taken by mouth with or without food. You can take one tablet at least half an hour ago before sexual activity. It may effective up to 36 hour. Do not take 2 dose of Tadalafil in one day.

HOW TADALAFIL WORKS: Tadalafil belong to a class of medicine called PDE5 inhibitors.
Tadalafil works by temporarily increasing blood flow to the penis when you get sexually excited.

CONTAINDICATION OF TADALAFIL: If you are a patient of multiple myeloma, Leukaemia, sickle cell anaemia, pigmentary retinopathy and hearing loss kindly avoid Tadalafil. Do not take this medicine if you have liver problem and severe renal impairment. Kindly avoid this medicine if you have restrictive cardiomyopathy.

PHARMACOKINETICS OF TADALAFIL: Tadalafil is rapidly absorbed after oral administration. Approximately half life of Tadalafil is 17.5 hours. Tadalafil is mainly metabolized by CYP3A4 to a catechol metabolite. Peak plasma concentration of Tadalafil is between 30 minutes and 6 hours. Tadalafil is excreted mainly in the feces (61% approximately) and approximately 36% excreted by urine.

SIDE EFFECTS OF TADALAFIL: Most common side effect of Tadalafil is headache, stomach upset, back pain, muscle pain, stuffy nose, flushing, or dizziness. In rare case patient may feel hearing problem or vision problem.

PRECAUTIONS: This product may contain inactive ingredients, which can cause allergic reactions so before taking tadalafil, tell your doctor or pharmacist if you are allergic to it.
If you are a patient of heart problem, kidney disease or liver disease kindly avoid this medicine. This drug may make you dizzy so kindly avoid alcohol or cannabis during the dose of Tadalafil.

CDSCO APPROVAL:
Tadalafil Tablet 2.5mg/5mg is approved by CDSCO in Indiain27.02.2013
Tadalafil tablet 20 mg (Additional Indication) is approved by CDSCO in India in 14.11.2009
Tadalafil Orally Disintegrating Strip 10mg & 20mg (Additional dosage form) is approved by CDSCO in Indiain 30.07.2014
Tadalafil 10mg/20mg Tablet is approved by CDSCO in India in 11.09.2003

FORMULATION AVAILABLE IN MARKET:
Tadalafil 20 MG tablets
Tadalafil 10 MG tablets
Tadalafil 5 MG tablets
Tadalafil 40 MG tablets
Tadalafil 20 MG /STRIP tablets
Dapoxetine 30 MG+Tadalafil 10 MG tablets
Tadalafil 2.5 MG tablets
Ambrisentan 5 MG+Tadalafil 20 MG tablets
Tadalafil 10 MG /STRIP tablet
Tadalafil 5 MG /STRIP tablet
Tadalafil 5 MG+Tamsulosin 400 MCG tablet

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk.

REFERENCES:

www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult