Valsartan Ip/bp/ep/usp

Here are the specifications for Valsartan according to various pharmacopeias (IP, BP, EP, USP):

Chemical Name: Valsartan
Molecular Formula: C24H29N5O3
Molecular Weight: Approximately 435.5 g/mol
Drug Class: Angiotensin II receptor antagonist
Mechanism of Action: Blocks the binding of angiotensin II to its receptors (AT1 receptors), resulting in vasodilation and decreased secretion of aldosterone.
Indications: Treatment of hypertension (high blood pressure), heart failure, and post-myocardial infarction.
Dosage Form: Oral tablets
Dosage: Typically administered once or twice daily; dosage varies based on patient response and condition.
Appearance: Valsartan is a white to practically white, odorless, crystalline powder.
Solubility: Sparingly soluble in water; freely soluble in ethanol; very slightly soluble in acetone.
Identification: Should meet the requirements specified in the respective pharmacopeias (e.g., IR spectrum, HPLC).
Purity: Should be not less than 98.0% (on dried basis).
Loss on Drying: Not more than 0.5%.
Residue on Ignition: Not more than 0.1%.
Related Substances: Should be within specific limits for related compounds.
Heavy Metals: Not more than 20 ppm.