Y-27632 Dihydrochloride
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We are offering our customers a wide range of Y-27632 Dihydrochloride, which are available following Specifications :-
Synonymsi Y-27632 2HCL
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Synonymsi Y-27632 2HCL
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We are offering our customers a wide range of Y-27632 Dihydrochloride, which are available following Specifications :-
Synonymsi Y-27632 2HCL
CAS No.i 146986-50-7
Molecular Formulai C14H21N3O.2HCl
Molecular Weighti 320.26
Solubilityi Soluble to 100 mM in phosphate buffered saline and to 100 mM in water
Appearancei White solid
Purityi >99%
CAS:146986-50-7
Chemical Name: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Biological ActivityY-27632 dihydrochloride is a selective Rho-kinase inhibitor, which suppresses cholinergic nerve-mediated contractions. In addition, studies show that Y-27632 dihydrochloride increases the release of neurotransmitters from cholinergic nerves. Studies conducted on smooth muscle preparations suggest that Y-27632 dihydrochloride suppresses nerve-mediated contractile responses stimulated by acetylcholine and noradrenaline. Furthermore, studies on lung tissue damage in rats suggest that Y-27632 dihydrochloride can restore the damage caused by oleic acid by inhibition of ROCK-1 and ROCK-2. Y-27632 dihydrochloride also inhibits protein kinase C related kinase, PRK2
Synonymsi Y-27632 2HCL
CAS No.i 146986-50-7
Molecular Formulai C14H21N3O.2HCl
Molecular Weighti 320.26
Solubilityi Soluble to 100 mM in phosphate buffered saline and to 100 mM in water
Appearancei White solid
Purityi >99%
CAS:146986-50-7
Chemical Name: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Biological ActivityY-27632 dihydrochloride is a selective Rho-kinase inhibitor, which suppresses cholinergic nerve-mediated contractions. In addition, studies show that Y-27632 dihydrochloride increases the release of neurotransmitters from cholinergic nerves. Studies conducted on smooth muscle preparations suggest that Y-27632 dihydrochloride suppresses nerve-mediated contractile responses stimulated by acetylcholine and noradrenaline. Furthermore, studies on lung tissue damage in rats suggest that Y-27632 dihydrochloride can restore the damage caused by oleic acid by inhibition of ROCK-1 and ROCK-2. Y-27632 dihydrochloride also inhibits protein kinase C related kinase, PRK2
Explore in hindi - Y-27632 डायहाइड्रोक्लोराइड
Company Details
Business Type
Exporter, Manufacturer
Establishment
2011
Seller Details
C
Chembest Bioscience Inc
sales Manager
Mr. Bruce Leung
Address
No.9300, Hunan Highway, Pudong, Shanghai, Shanghai, 201300, China
Pharmaceutical Chemicals in ShanghaiReport incorrect details
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