99.9% Pure Quinine Hcl Usp Application: Pharmaceutical

Quinine is derived from the stem of cinchona (quina-quina) tree. Besides quinine hydrochloride is an alkaloid having kinds of applications in the field of medicine. Quinine hcl is a basic compound with aryl amino alcohol group.

Application of Quinine:
1. Quinine is a natural white crystalline alkaloid that fluoresces under direct sunlight.
2. Quinine is also a mild antipyretic analgesic and can also be used as an ingredient in common cold medicine.
3. Quinine hydrochloride is generally used as a bitter and flavoring agent, and can still be used to treat Brazilian shellfish.
4. Quinine hydrochloride is also used in certain muscle diseases, such as nocturnal leg cramps and congenital muscle rigidity, because quinine can directly act on the myometrium and sodium channels.
5. Reducing oxygen intake and carbohydrate metabolism is one of the effects of quinine, because it can reduce the excitability of muscle fibers by changing the distribution of calcium. It can also help improve the efficacy of certain antitumor drugs.

Biochem / Physiol Actions:-
Quinine hcl is widely used in the treatment of malaria. It possesses erythrocytic and gametocytocidal action against Plasmodium sp.
Quinine also serves as an analgesic drug. Upon administration, quinine hcl is present mostly bound to A A -1 acid glycoprotein in the body fluids.
Furthermore, Quinine has the ability to cross the placenta and the blood brain barrier. Quinine has a half-life of 11-18 hours.

Side effect:-
TinnitusA A A
hearing defectsA A A
nausea A A A
headache are some of its side effects.
Quinine base in various salts

Quinine base : 100 mg
Quinine bisulfate : 169 mg
Quinine dihydrochloride : 122 mg
Quinine gluconate : 160 mg
Quinine hydrochloride : 111 mg
Quinine sulfate dihydrate [(quinine)2H2SO4AcA A 2H2O] : 121 mg