Rasagiline Ip/bp/usp/ep Application: Medicine

Niksan Pharmaceutical and the Niksan group companies are the worlda s most leading pharmaceutical companies in the manufacturing, supplying and exporting of the Rasagiline API and also finished formulation of Rasagiline. Niksan Pharmaceuticala s Rasagilineproduct appreciated widely by our group companies and by the customers all around the world.

Niksan Pharmaceutical provides API and finished formulations of Rasagiline in many Indian states of like Karnataka, Tamil Nadu, Telangana, Maharashtra, Rajasthan, Sikkim, Tamil Nadu, Goa, Gujarat, Jammu and Kashmir, Andhra Pradesh, Telangana, Punjab, Maharashtra, West Bengal and many other states.

Niksan pharmaceutical is also large exporter of the API and finished pharmaceutical products of Rasagiline in many countries for years. The countries where we exporting are Puerto Rico, United States, Ireland, Israel, United Kingdom, United States, Australia South Korea, Hong Kong, Taiwan, France , Canada, Bangladesh, Poland, Pakistan, Thailand, Netherlands, Turkey, Vietnam, Philippines, India, Iran, Canada, Indonesia, Finland, Thailand, Egypt, Vietnam, UK, Taiwan, Netherlands, Poland, Australia, Mexico, Germany etc.

Rasagiline is irreversible inhibitor of monoamine oxidase-B which is used to treatment of early Parkinson's disease and also used to treatment of nerves system disease.

SYNONYMS: Rasagilina, Rasagiline

IUPAC NAME:(1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine

CAS NO: 136236-51-6

FORMULA: C12H13N

MOLECULAR MASS: 171.23 g/mol

STORAGE OF RASAGILINE: Store it in room temperature (20A C to 25A C). Store it in cool and dry place, away from moisture and direct light. Do not store this medicine in bathroom or any humidly place.

APPLICATIONS OF RASAGILINE: Rasagiline used to treatment of Parkinson's disease. It is also reduce the amount of off time (periods of slow movement or stiffness).

HOW TO USE: Rasagiline is taken by mouth with or without food. Take regular dose for better result. Follow all direction on your prescription label. Ask your doctor if you have any confusion about Rasagiline medication.

HOW RASAGILINE WORKS: Rasagiline works by increasing the amounts of certain natural substances in the brain.

CONTRAINDICATIONS: If you are a patient of malignant melanoma and skin cancer kindly avoid Rasagiline. Do not take Rasagiline if you have manic-depression and psychotic disorder. Kindly avoid Rasagiline if you have any liver problem or high and low blood pressure problem.

PHARMACOKINETICS OF RASAGILINE: Rasagiline rapidly absorbed after oral administration. Half life of Rasagiline is 3 hours. Rasagiline plasma protein binding ranges is 88-94%. Peak plasma concentration of Rasagiline is 2.5 mg/ml to 4.9 mg/ml. Almost All Rasagiline and its metabolites eliminate by liver.

SIDE EFFECTS OF RASAGILINE: Common side effects of Rasagiline are Dizziness, drowsiness, joint pain, heartburn, nausea, dry mouth and weight loss. This medicine may cause serotonin syndrome. In the rare case this medicine may cause high blood pressure. The very serious allergic reaction to this medicine is rare but you see any side effect of Rasagiline kindly tell your doctor.

PRECAUTION: During the pregnancy kindly avoid Rasagiline. Before the medication share your past medical history with your doctor. This medicine may make you dizzy so kindly avoid alcohol and cannabis. Consult with your doctor before the breast-feeding because it is unknown if drug passes into breast milk. If you have any liver disease and mental disorder kindly tell your doctor before taking Rasagiline.

CDSCO APPROVAL: Rasagiline (as mesylate) Tablets 0.5mg/1mg is approved by CDSCO in India in 31.01.09.

FORMULATIONS AVAILABLE IN MARKET:
Rasagiline 1 MG piles
Rasagiline 0.5 MG piles
Rasagiline (as mesylate) Tablets 0.5mg/1mg

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk.

REFERENCES:

www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult