Medicine Raw Materials Nicorandil Ip/bp/ep/usp

Niksan Pharmaceutical is the worlda s top most pharmaceutical company who manufacturer, supplier and exporter of Nicorandil among the all the pharmaceutical companies. We provide best Nicorandil API and finished formulations to our customers as well as our group companies. Our product Nicorandil is esteemed and praised by clients and also by other companies.
Niksan Pharmaceutical is the largest manufacturer, trader and supplier of Nicorandil in all-over Ankleshwar, Gujarat, India.
Niksan Pharmaceutical manufacture and supply the Nicorandil product to the Indian states like Maharashtra, Goa, Sikkim, Assam, Punjab, Delhi, Bihar, Karnataka, Meghalaya, Tamilnadu, Kerala, Gujarat, Haryana, Rajasthan, Madhya Pradesh, Uttar Pradesh, Rajasthan, Karnataka, and other states.
Niksan Pharmaceutical is manufacturer, supplier and exporter of Nicorandil in many countries from many years like Myanmar (Burma), Sri Lanka, United Kingdom, Taiwan, Australia, Lebanon, Iran, New Zealand, Egypt, Ireland, Vietnam, Pakistan, South Korea, Austria, Iraq, France, United Arab Emirates, Philippines, Romania, Saudi Arabia, Malaysia, Switzerland, Spain, Canada, Italy, Germany, United States and many more countries.
Nicorandil is drug belongs to the antianginal type of medicine. Nicorandil used in the treatment of angina.
WHAT IS ANGINA: It a chest pain caused by heart problem, myocardial problem or coronary artery disease.
Nicorandil is prescribed by doctors when the other heart medicine is not suitable for you.
Nicorandil increase the blood flow to the heart and by this Nicorandil helps to reduce the angina problem. Taking Nicorandil regularly may also prevent the other heart problems.
SYNONYMS: Nicorandil, Nicorandillum.
IUPAC NAME: 2-[(pyridin-3-carbonyl) amino] ethyl nitrate
CAS NO: 65141-46-0
FORMULA:C8H9N3O4
MOLECULAR MASS: 211.17 ga cmola 1
STORAGE CONDITIONS: Store in cool and dry place away from direct light. Do not put in fridge or in bathroom or any humid place. Keep away from the children and pets.

HOW TO USE: Take medication with water or milk. Take medication orally with or without food. If you have difficulty to swallow tablet, break the tablet in two pieces and after swallow it.

HOW NICORANDIL WORKS: Nicorandil opens and relax the blood vessels and by this the blood flow to the heart increases and by this it reduces the angina problem and other heart related problem.
PHARMACOKINETICS OF NICORANDIL: Nicorandil is the potassium channel opener drug, and by this Nicorandil cause vasodilation of the blood vessels. Because of vasodilatation of the blood vessels the blood flow into heart increases and prevents the heart problem. Nicorandil well absorbed after oral administration, and absorbed in GI track and reaches its peak plasma concentration in 30to60 minutes. The bioavaibility of Nicorandil is 75%. The half-life of Nicorandil is approximately 1 hour. Only 1% of Nicorandil is excreted unchanged by the urination.

SIDE EFFECTS OF NICORANDIL: The common side effects of Nicorandil are headache, flushing, nausea, vomiting, felling sick, and dizziness. If the serious side effects like stomach ulcers, paining eye, eye ulcer, pain on skin, blood in your stool being sick, and loss of appetite contact you doctor and tell about the problems.

PRECAUTIONS: Kindly tell your doctor if you have any allergic reaction to Nicorandil. If you see any side effects of Nicorandil inpatient contact your doctor. Tell your doctor about past disease like liver, kidney problems. If you are already taking the other medication kindly take your doctora s advice. Nicorandil makes you dizzy so do not drive vehicles or do any heavy exercise. Do not take medication if you are pregnant or willing to become pregnant.

CDSCO APPROVAL: Nicorandil tablets/bulk approved by CDSCO in India in 10.01.1997,
Nicorandil E.R Tablet (10mg/20mg) approved by CDSCO in India in 24.04.2006.
FORMULATIONS AVAILABLE IN MARKET:
Nicorandil 5mg tablets
Nicorandil 10mgm tablets
Nicorandil 20mg tablets
Nicorandil 48mg tablets
Nicorandil 2mg injections

Note: Product protected by valid patents are not offered for sale in countries where such patents are still valid and its liability is at Buyers Risk.

REFERENCES:
www.webmd.com
https://pubchem.ncbi.nlm.nih.gov
https://go.drugbank.com
https://cdscoonline.gov.in
https://www.wikipedia.org/
https://www.drugs.com
https://www.zaubacorp.com
https://www.practo.com/consult